Anxiety, depression and distress outcomes from the Health4Life intervention for adolescent mental health: a cluster-randomized controlled trial

——原载《自然 – 心理健康》2024年第2卷第3期——

<Nature - Mental Health> Volume 2, Issue 7, 2024

【摘要】精神障碍是全球疾病负担的主要原因。由于发病通常发生在青春期，因此在此期间预防至关重要。Health4Life学校多项健康行为改变 (MHBC) 干预针对六种生活方式风险因素：饮食、睡眠、身体活动、屏幕时间、饮酒和吸烟。Health4Life已在71所澳大利亚学校（6,639名七年级学生）的集群随机对照试验中进行了评估。本研究展示了干预对抑郁、焦虑和心理困扰症状的次要结果的影响。对基线，干预后（7周）、12个月和24个月的数据进行广义线性混合效应分析表明，在24或12个月的随访中，Health4Life干预在减少抑郁、焦虑或心理困扰症状方面并不比主动对照更有效；然而，干预后立即对心理困扰和抑郁症状有短期益处。这项研究提供了新的证据，表明多种健康行为改变干预措施可能会改善青少年的心理健康，但未来的研究应该探索解决焦虑和维持长期效果的方法。

[Abstract] Mental disorders are a leading cause of disease burden worldwide. As onset typically occurs in adolescence, prevention during this period is critical. The Health4Life-school-based multiple health behavior change (MHBC) intervention targets six lifestyle risk factors: diet, sleep, physical activity, screentime, alcohol use and smoking. Health4Life has been evaluated in a cluster-randomized controlled trial in 71 Australian schools (6,639 grade seven students). This study presents intervention effects on secondary outcomes of depressive, anxiety and psychological distress symptoms. Generalized linear mixed-effect analyses of data from baseline, post-intervention (7 weeks), 12 months and 24 months showed that the Health4Life intervention was no more effective than an active control in reducing depressive, anxiety or psychological distress symptoms at a 24 or 12 month follow-up; however, there were short-term benefits for psychological distress and depressive symptoms immediately post-intervention. This study offers new evidence that multiple health behavior change interventions may improve adolescent mental health, but future research should explore methods to address anxiety and sustain effects over the longer term.

论文原文：S. Smout, K. E. Champion, S. O’Dean, M. Teesson, L. A. Gardner & N. C. Newton (2024).  Anxiety, depression and distress outcomes from the Health4Life intervention for adolescent mental health: a cluster-randomized controlled trial. Nature - Mental Health, Volume 2, Issue 7, Pages 818–827.

https://doi.org/10.1038/s44220-024-00246-w

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